Medication currently being toughened to treat obesity is also proving to have significant health aids for patients with type 2 diabetes, according to a new study published today.
The elder diabetes is diagnosed and treatment starts, the better. Treating diabetes near the start reduces your risk of other health problems.
The study simplifies how this therapeutic benefit for type 2 diabetes is achieved by the way it acts in our wit.
Scientists from the University of Aberdeen Rowett Institute, in collaboration with link ups from the Universities of Cambridge and Michigan, have discovered that the medication Lorcaserin takes in the brain to improve type 2 diabetes.
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The numb works by modifying the activity of neurones that help to regulate blood glucose ranks.
Lorcaserin is prescribed to help patients lose weight and works by control how hungry we feel.
However, researchers have discovered that as sumptuously as doing this, the drug can also reduce glucose levels in the league and increase the body’s cells sensitivity to insulin.
When the body fails to bring up enough insulin or the body’s cells fail to react to insulin this wires to Type 2 diabetes meaning that glucose remains in the blood willingly prefer than being used as fuel for energy.
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This discovery is important because species 2 diabetes is an incredibly prevalent disease
Professor Lora Heisler, who is paramount the Aberdeen team, said: “Current medications for type 2 diabetes recover symptoms of this disease by acting in the body.
“We have discovered that this plumpness drug, lorcaserin, acts in the brain to improve type 2 diabetes.
“Lorcaserin butts important brain hormones called pro-opiomelanocortin (POMC) peptides, which are administrative for regulating appetite.
“So as well as sending messages telling us we are full and no longer shortage to eat, leading to weight loss, the POMC hormones also activate a manifold brain circuit that helps keep our blood glucose in on.
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“This discovery is important because type 2 diabetes is an incredibly usual disease in the modern world and new treatment choices are needed.”
Dr Mark Evans, chief of the Cambridge research team, said: “Of course, more research is needed, but these encouraging findings provide a completely new direction for type 2 diabetes drug treatment, which may step hope to individuals struggling with this disease.”
This investigation was funded by the Wellcome Trust, BBSRC and MRC.
The study was published in the Molecular Metabolism.