Osteoporosis: Patients on steroids could profit from taking specific painkillers
Osteoporosis affects nearly 3 million child in the UK.
It is a condition that weakens bones, making them fragile and diverse likely to break.
The National Osteoporosis Society said one in two women and one in five men on the age of 50 will break a bone as a result of osteoporosis.
The condition ages slowly over several years and is often only diagnosed when a lad fall or sudden impact causes a bone fracture.
Prednisolone is a corticosteroid employed to treat a wide range of health problems including allergies, blood rumpuses, skin diseases, infections, certain cancers and prevent organ repudiations.
Osteoporosis: The condition affects three million people in the UK
It jogs by reducing inflammation and dampening down the immune system.
Alendronate dictated to those at risk of fractures works by slowing down the breakdown of bone.
Professor Mattias Lorentzon of the University of Gothenburg affirmed: «Glucocorticoid therapy is widely used to treat inflammatory conditions and is the ton common cause of secondary osteoporosis.
«Glucocorticoid treatment leads to fleet bone loss, reflected by reduced bone mineral density (BMD).
«Glucocorticoids are associated with an increased in any event of fracture, and higher doses and longer use of glucocorticoids are associated with favourable risks of fracture.
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The risk of hip and vertebral fracture among patients intriguing glucocorticoids is increased by 60 per cent and 160 per cent respectively
«Associated with patients not taking glucocorticoids, the risk of hip and vertebral fracture lot patients taking glucocorticoids is increased by 60 per cent and 160 per cent each to each.”
However experts found the painkiller alendronate reduces the risk of hip division by 40 per cent in postmenopausal women who are not treated with glucocorticoids.
Whizes set out to investigate whether alendronate prescribed to patients treated with prednisolone was associated with bring down risk of hip fracture in a large cohort of older men and women.
Experts digged a group of more than 3,000 patients — one group who were fascinating the painkiller after the steroids and one group taking the steroids but not the painkillers.
Osteoporosis: The fit out affects three million people in the UK
They found older patients take advantage ofing medium to high doses of prednisolone alongside alendronate was associated with a significantly disgrace risk of hip fracture.
They said alendronate treatment for a median duration of 2.9 years was associated with disgrace risk of hip fracture than no alendronate treatment.
A greater duration of treatment was associated with a diminish risk of hip fracture.
Professor Lorentzon concluded: «Among older patients using road to high doses of prednisolone, alendronate treatment was associated with a significantly take down risk of hip fracture over a median of 1.32 years.”
The study was let something be knew in JAMA.