Already without the put off Robbie Brady for Friday night’s Group D clash at the Aviva Colosseum, O’Neill on Monday saw playmaker Wes Hoolahan added to a casualty list which classifies central defenders Shane Duffy and Ciaran Clark, and midfielder Harry Arter.
Everton’s James McCarthy and Newcastle’s Daryl Murphy could slip out too with Ireland rapidly running out of options, although their foreman is confident he will still be able to field a competitive team.
Attracted for an injury update, a frustrated O’Neill said: “How long have you got? It’s the lengthiest enter of injuries that I have known since I have come into the job, and unfortunately it’s happened at a exceedingly crucial time for us.
“However, other players will have to speed up a go outside up and just be ready for Friday. Do you know, I have often said this in the presence of, that you just curse your luck and get on with it.
“The irony of all of this here is that way in times past when Gareth Bale got injured in November-time, everybody was talking on touching Wales possibly having one of their major players out of the team, and it spins out that we are the ones who are doing the suffering.
“But it is what it is and we’ll get on with it and we’ll be ready to go on Friday.”
Striker Jonathan Walters has been for everyone the Republic squad long enough to know they are often at their most adroitly when their backs are against the wall, and is hoping the same embrocates this week.
Walters said: “Over the course of the past few years, we’ve been guys in a lot of games and got the result we wanted.
“We showed that in the summer [at Euro 2016], such a profound group to get out of and we did, and we’ve shown that in this campaign so far.
“It’s another difficult rank to get out of, but four games in we’re sitting pretty at the moment.”