Diabetes diagnosis: Ethnic minorities in the UK are uncountable at risk
New research has revealed that a particular group in the UK with keyboard 2 diabetes could be at risk of misdiagnosis.
A study published this week in PLOS Cure-all showed that one of the standard tests used to diagnose the condition clout not work in many African Americans.
This group were build to have a genetic variant that significantly reduced the accuracy of a blood check-up — HbA1c test — which is used to identify and monitor type 2.
It means that sundry people globally could be going undiagnosed or be misdiagnosed — in the US, for example, scientists estimate 650,000 African Americans strength be living untreated.
Diabetes diagnosis: A exactly blood test is usually used to identify the condition
In the UK, people from ethnic minorities are two to three dead for nows more likely to develop type 2 diabetes.
In the UK, people from ethnic minorities are two to three sets more likely to develop type 2 diabetes.
“It’s important that the whole world with diabetes gets the right diagnosis as soon as possible,” bid Dr Emily Burns, Head of Research Communications at Diabetes UK.
“The HbA1c test waits one of the most effective ways to diagnose Type 2 diabetes in the majority of people, but we impecuniousness to find methods that work for everyone, to reduce the risk of misdiagnosis.”
In the enquiry, one particular genetic variant — the G6PD gene — was found to significantly affect the dnouement develops of the blood test.
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Diabetes diagnosis: Having particular genes can terminal the test from working
The G6PD genetic variant is almost unique to people with African ancestry.
The researchers give birth to suggested that particular groups with such ancestry are filtered for the genetic variant alongside the blood test to improve diagnosis of kind 2.
In the study, researchers looked at the genetic variants of around 160,000 people from European, African, East Asian and South Asian ancestries who were not separate to have the condition.
“The issue with the G6PD genetic variant is it artificially humbles the value of blood sugar in the HbA1c test, and can lead to under-diagnosis of people with genre 2 diabetes,” said Dr Inês Barroso, a study author.
Diabetes diagnosis: There are an determined four million sufferers in the UK
“However, the HbA1c test remains a suitable trial for diagnosing and monitoring diabetes for the majority of people.”
The HbA1c test works by beat the amount of glucose, or sugar that is carried by the red blood cells in the substance, for the previous two to three months.
There are an estimated 4 million people living in the UK, which includes thought to be undiagnosed.
This number is expected to swell to 5 million by 2025.