Diabetes can be reversed in a matter of weeks by following a strict low calorie regime, shows research
Scientists say lifestyle driven Type 2 — a condition that approximately 12 million Britons are thought to be at risk of developing — is caused by surplus fat in the liver and pancreas.
Findings due to be presented today have given blooming hope that the debilitating disease need not to a life sentence.
They crow about that even if sufferers have been blighted for years the up can be brought under control by sensible eating.
Professor Roy Taylor, from Newcastle University, suggested: “The good news for people with Type 2 is our work shows that settle accounts if you have had the condition for 10 years you are likely to be able to reverse it by motile that all important tiny amount of fat out of the pancreas. At present, this can no more than be done through substantial weight loss.”
The good news for people with Type 2 is our work teaches that even if you have had the condition for 10 years you are likely to be qualified to reverse it by moving that all important tiny amount of fat out of the pancreas
Nine in 10 Paradigm 2 sufferers are overweight or obese and do not produce enough insulin, or the insulin they spark does not work properly.
Professor Taylor, who has spent 40 years chew overing the condition, will deliver his research to an international collaboration of experts at the European Society for the Study of
Excess calories leads to extravagance fat in the liver, says Professor Taylor
Excess fat in the liver is passed on to the pancreas, calling the insulin producing cells to fail.
He says losing less than 1 gram of fat from the pancreas finished with diet can re-start normal production of insulin, reversing Type 2.
And he says this corpses possible for at least 10 years after the onset of the debilitating blight.
Professor Taylor said: “I think the real importance of this act on is for the patients themselves.
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“Uncountable have described to me how embarking on the low calorie diet has been the only opportunity to prevent what they thought — or had been told — was an inevitable ebb into further medication and further ill health because of their diabetes.
“By working the underlying mechanisms we have been able to demonstrate the simplicity of Standard 2.”
The diabetes epidemic griping Britain costs the NHS more than £10 billion a year — 10 per cent of its budget — with one in the flesh diagnosed every two minutes.
A decade ago no child in Britain had Type 2 but there are now assorted than 500.
They are twice as likely to have a heart attack and three times as promising to have kidney disease.
The diabetes plague in Britain costs the NHS more than £10 billion a year
The billion of new diagnoses has rocketed by almost 75 per cent in a decade.
The number of adults with the bug has risen by 1.5 million in the past 10 years, with GPs blasting 3.6 million have the condition.
There has been an increase of 137,000 in the since year alone.
The latest research backs up previous studies which demonstration how keeping calorie intake low can improve health.
In a recent trial funded by Diabetes UK all join ins reversed their diabetes by drastically slashing their food intake to impartial 600 calories a day for two months.
And three months later, seven balanced free of diabetes.Eleven people who had developed diabetes later in duration were put on an extreme diet of just 600 calories a day consisting of clear diet drinks plus 200 calories of non-starchy vegetables.
A MRI explore in depth of their pancreas revealed the fat levels had returned from an elevated even to normal, regaining the ability to make insulin and as a result, blood sugar after dinners steadily improved.
Prof Taylor’s research confirms his Twin Succession Hypothesis that Type 2 is caused by excess fat within both end and pancreas.
As insulin controls the normal process of making glucose, the liver then bring forwards too much glucose.
Simultaneously, excess fat in the liver increases the normal process of export of fat to all series.
In the pancreas, this excess fat causes the insulin disclosing cells to fail
In the pancreas, this excess fat causes the insulin exhibiting cells to fail.
An earlier study confirmed that if excess comestibles intake was sharply decreased through a very low calorie diet, all these deviant factors would be reversed.It showed a profound fall in liver fat gratify resulting in stablilisation of hepatic insulin sensitivity within seven days of starting a darned low calorie diet.
Fasting plasma glucose became normal in a week and once again eight weeks, the raised pancreas fat content fell and normal insulin transudate became re-established, with normal blood glucose control.
Prof Kamlesh Khunti, of the Leicester Diabetes Middle, said: “This is great research and shows that low calorie reduces can work in highly-motivated people, however, this would be difficult to put into effect widely for most people.”
Chris Chapman, director of diabetes body GlucoRx, said: “I was diagnosed with Type 2 in 2011 but after be guided by a personal programme involving diet and physical activity I am close to tender the condition into remission, so I fully support the findings of this analyse.”